Neuro Protection of Calotropis Procera Leaf Extract in Neuropathy-Induced Rat Model

Abstract

Objective: To assess and validate the neuroprotective effect of the Calotropis procera leaf extract for safe use in traditional medicine. Method: Ethanolic leaf extract of Calotropis procera was tested in neuropathy-induced rat model with two different doses; high dose (77mg/kg) and low dose (36.5mg/kg). Results: The studies revealed that in group 3 and 4 Calotropis procera leaf extract treated animals have shown neuroprotective effect. Conclusion: The extract significantly mitigated the effects of neuropathy in rats and shown neuroprotective action.