Meta Analysis Study of Environmental Pollution and Its effect on Human Brain Behaviour

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Fahhad Mohammed Atallah Alanazi, Meshal Abdullah Ali Eid, Suhail Fahd Abutalib, Mohammed Ahmed Mohammed Asiri, Ashwaq Saleh Mohammed Alanazi, Khalid Mohammed Mudghir Alshamrani, Musallam Furayj Saeed Alatawi, Majed Abdullah Salem Al Mohammadi, Omar Saad R Almutairi, Nehad Abdulrhman Almohmadi, Ahmad Dakhiallah Alharbi, Mazen Mohammad Alofi, Naif Saad J Alharbi, Ali Saleh Almatrafi

Abstract

Background: The effects of ambient air pollution on brain behaviours are poorly supported by epidemiological research. The aim of this study was to ascertain if changes in brain behaviours and exposure to air pollution are related. Methods: Between duration of March 2022  and April 2022, a thorough search of the literature was done using databases, including Google scholar. The PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analysis) statement served as the foundation for the current study's approach.  Results: The results of the publication bias of the study indicated the absence of bias in the examined results (p = 0.431).  There was a relationship between NOx index and brain behaviour, but this correlation was not significant (RR = 1.36, 95% CI 0.93–1.48, P = 0.163; Q-value = 42.33, df = 7; I2 = 59.69 %, P = 0.108). Conclusion: In summary, our findings offer more, albeit conflicting, proof of the harmful effects of air pollution on cognitive brain development, which is largely in line with mechanistic data and other published studies. Nevertheless, no correlation was found between the brain behaviour and other air contaminants. However, further research is required to more precisely define the hazards, particularly with regard to particular contaminants and the crucial exposure times.

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