Structural characterization of novel Schiff base compounds: Investigation of their Spectral, Thermal, Structural, Morphological and biological studies

Abstract

: A novel Schiff bases have been synthesized by reacting 4, 4’- diaminodiphenyl ether with R-substituted salicylaldehyde (R= H, 5-Br and 3-OCH₃) and 2-hydroxy -1- naphathaldehyde. They were characterized by spectral (UV-VIS., FTIR, NMR and Mass), thermal and XRD analyses and also tested for the evaluation of biological activities. The TG curves of the Schiff bases were critically analyzed to estimate various kinetic parameters (n, E, Z, ΔS and G) using Coats – Redfern (C.R.) method. The values of E and G are sufficiently high and indicate that the Schiff bases are thermally stable. X-ray Diffraction studies suggest monoclinic crystal system to all Schiff bases. The scanning electron microscopic study reveals that the surface of Schiff base is without crack hole and homogeneous. The biological studies suggest that the all Schiff bases possess excellent antibacterial activity against B. subtilis and

1. coli, antifungal activity against A. Niger and C. Albicans.