Formulation and Pharmacological Evaluation of Herbal Ointmentcontaining Curcuma Caesia & Piper Nigrum

Abstract

The annual herb Curcuma caesia Roxb has large leaves. Traditional medicine uses rhizomes. Fresh rhizomes smell camphoraceous. According to accounts, Camphor, (Z)-ocimene, ar-curcumin, 1,8-cineole, elemene, borneol, and bornyl acetate are all major components of this plant. The herb has been claimed for its antifungal, anti-asthmatic, smooth muscle relaxant, antibacterial, antioxidant, analgesic, locomotor depressant, anticonvulsant, and anti-inflammatory qualities. It is now a major source of natural chemicals for drug development. Topical ointments are more suitable since patients comply betterowing to antioxidants and anti-inflammation. Curcuma Caesia may revitalise skin by restoring its natural radiance. Similarly, Piper nigrum treats acne and skin infections with antibacterial and anti-inflammatory effects. Trituration was used to make ointment from an oily base. The formulation also contained 0.7gm Curcuma Caesia and 0.2gm piper nigrum extract.The physicochemical parameters revealed good spreadability, extrudability, washability, solubility, drying loss, and others. The formulation was further tested for stability at 2°C, 25°C, and 37°C for four weeks. Spreading ability, diffusion research, and irritating effect did not change. Thus, an ointment using Curcuma Caesia and piper nigrum extract could effectively exploit these herbs' therapeutic capabilities.